Each Biome and Beyond ozone suppository holds 2.6 mL of fully ozonated olive oil. They are created using a cold plasma ozone generator with medical oxygen. The benefit of using cold plasma (low frequency) ozone when producing ozonated oil is that no heat enters the oil. Traditional ozone generators (high frequency) produce heat upwards of 250 degrees which enters the oil and can cause it to lose some of its beneficial properties. Comes in jars of 30. Ingredients: Fully ozonated organic olive oil, organic cocoa butter, medical grade ozone Different oils hold different amounts of ozone. This is determined using the potential ozonide intensity factor. This is measured by looking at the omega 3, 6, 9 fatty acids that the particular oil holds. Oils with higher omega 9 fatty acids hold more ozone. Olive oil is roughly in the middle of the potential ozonide intensity scale. The ozone suppositories must be stored in the refrigerator or freezer so they will last longer and are easier to use. Ozonated oil has been known to last over ten years when refrigerated. THESE NEED TO BE INSERTED IMMEDIATELY ONCE REMOVED FROM THE REFRIGERATOR OR FREEZER AS THEY LIQUEFY QUICKLY. Return policy: 30 day money back Guarantee
Each Biome and Beyond ozone suppository holds 2.6 mL of fully ozonated olive oil, and a proprietary blend of clincally proven essential oils and probiotics.
Comes in jars of 30.
Ingredients: Fully ozonated organic olive oil, organic cocoa butter, medical grade ozone, Lemongrass Essential Oil, Thyme Essential Oil, Lavender Essential Oil, Bacillus Coagulans probiotic.
Different oils hold different amounts of ozone. This is determined using the potential ozonide intensity factor. This is measured by looking at the omega 3, 6, 9 fatty acids that the particular oil holds. Oils with higher omega 9 fatty acids hold more ozone. Olive oil is roughly in the middle of the potential ozonide intensity scale.
We recommend storing ozone suppositories in the refrigerator so they will last longer and are easier to use. Ozonated oil has been known to last over ten years when refrigerated. It is highly recommended placing into a refrigerator immediately upon receiving to help preserve freshness.
Ozonated Olive Oil
Human studies that compared Ozonated olive oil to prescription antifungal creams, suggested Ozonated olive oil as a safe and effective natural alternative to these drugs. Especially in cases of vaginal yeast infections.
Results • Ozone and clotrimazole both reduced symptoms significantly and led to a negative culture for vaginal candidiasis (P < .05). No significant differences existed between the 2 groups in their effects on the symptom of itching and leucorrhea and on the results of the culture (P > .05).
Ozonated olive oil was also shown to be gentle enough for cases of mouth irritation and gum infectionsand various skin issues.
LEMONGRASS ESSENTIAL OIL
Lemongrass contains several biocompounds in its decoction, infusion and essential oil extracts. It is an Anti-oxidant, anti-inflammatory, anti-bacterial, anti-fungal, anti-obesity, antinociceptive, anxiolytic and antihypertensive. Evidences of lemongrass were clearly elucidated to support initial pharmacological claims. In addition Lemongrass is non-toxic and non-mutagenic.
In one study, The antibacterial and antifungal activity of ten essential oils was tested against a range of vaginal bacterial and fungal strains isolated from existing vaginal infections including Atopobium vaginae, Gardnerella vaginalis, Bacteroides vulgatus, Streptococcus agalactiae, H2O2-producing lactobacilli and non H2O2-producing lactobacilli, Candida albicans, Candida glabrata, Candida parapsilosis and Candida tropicalis. Investigation of the in vitro susceptibility of the essential oils against bacteria revealed that lemongrass, tea tree and lavender exhibited the lowest minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) at 1-2.5 μl/ml, thus being the most potent essential oils against the tested bacteria.
THYME ESSENTIAL OIL
Bacterial vaginosis (BV) is the most frequent diagnosis made in women with lower genital tract symptoms. It has recently been observed that 90 % of subjects with BV show the growth of bacteria in the form of biofilms as against only 10% without BV, and that Gardnerella vaginalis was the predominant species. The propensity of G. vaginalis to form biofilm is clinically relevant because this form of growth allows it to tolerate higher concentrations of certain antibiotics, thus increasing the possibilty of recurrent BV even after apparently curative therapy. One study found that thymol, a molecule present in thyme essential oil, is credited with having a series of pharmacological properties including antimicrobial and antifungal effects, can interfere with newly formed and mature G. vaginalis biofilms.
LAVENDER ESSENTIAL OIL
The treatment of candidiasis infections is an important problem in the health care system. One study investigated the in vitro effect of lavender essential oil and clotrimazole(pharmaceutical antifungal) on isolated C. albicans from vaginal candidiasis. At 48 hours the average fungal cell count was lower in lavender group. In addition, the lavender had no negative impact on the healthy vaginal flora while the clotrimazole has a deleterious effect on the beneficial bacteria.
Disruption of vaginal microbiota equilibrium promotes infectious clinical syndromes with annoying symptoms, such as vaginal discharge, odour, irritation, pruritus, and vulvar burning. Although identifying and eradicating the pathogen involved has been the standard of care, regional microbiota restoration with probiotics has been gaining ground in recent years. This study aimed to assess the effectiveness of topical Bacillus coagulans treatment for patients exhibiting vaginal discomfort symptoms. A clinical trial was conducted on the use of a topical B. coagulans regimen among reproductive-age women with vaginal discomfort symptoms. We assessed their symptoms using a questionnaire, measured vaginal pH, and performed vaginal swabs for microscopy and cultivation. Over the next 4 days, patients received B. coagulans vaginal douches and suppositories with appropriate antibiotic treatment being added on the fourth day based on vaginal swab results. Patients returned 16 days later to fill out in the questionnaire again. The Wilcoxon signed-ranked test was then used to assess differences in symptomatology and pH between appointments. A reduction in vaginal pH was reported between the first and second visit (P<0.001). The probiotic regimen exerted a major beneficial effect in all vaginal manifestations: vulvovaginal itching, burning sensation, vaginal irritation, and vaginal discharge. Additionally, three out of the four symptoms were alleviated to a greater extent during the first four days of exclusive probiotic use than during the second phase. Our sample provided significant results regarding the benefits of B. coagulans for vaginal discomfort. We postulate that the greatest symptom improvement was achieved within the first 4 days of exclusive probiotic use, before the addition of antibiotics. This study agrees with the increasing literature on the contribution of probiotics toward vaginitis treatment.
In addition, B. subtilis reduced the biofilm formation and filamentation of C. albicans by negatively regulating the ALS3, HWP1, BCR1, EFG1 and TEC1 genes that are essential for the production of biofilm and hyphae.